circRNA basic information
circBase ID: -
Name: mmu_circ_Zfp609
Synonym: -
Host Gene: Zfp609
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005575
MONDO name: colorectal cancer
Disease details: colorectal cancer
Disease DO ID:
 5672, 9256
Disease MeSH ID:
 -
Disease NCIt ID:
 C4978
Disease ICD11 ID:
 -
Disease OMIM ID:
 114500
Species: Mouse
Species details: Mus musculus
Tissue specimen:

subcutaneous tumor
Cell lines:

CMT93.hCG.Luc; CMT93
In vivo animal model:

syngeneic model
circRNA-disease information
Expression pattern:
UN
Associated gene: -
Associated microRNA: -
Biological function: promotes tumor growth in vivo
Molecular mechanism: not specified
Biological pathway or process:

proliferation (promotes)
Detected method:
Q
B
Validation methods:

RT-qPCR; Northern Blot; Transfection; In Vivo Animal Model
Clinical significance:

-
Description:

In mouse CMT93 cells and C57BL/6 syngeneic tumors, circZfp609 overexpression increases tumor growth, supporting an oncogenic role consistent with circZNF609 findings. The paper does not report an endogenous differential-expression direction for circZfp609 during disease progression.
Confidence score:

0.4062
Other information
Title:

Gene Expression Signatures of a Preclinical Mouse Model during Colorectal Cancer Progression under Low-Dose Metronomic Chemotherapy.

Journal: Cancers
Published: 2020
PubMed ID: 33375322
Study type:

biological research
Data availability: GSE163076
Code availability: -