circRNA basic information
circBase ID: hsa_circ_0005070
Name: hsa_circ_UBR5
Synonym: -
Host Gene: UBR5
Genomic location(hg19): chr8:103341317-103357773:-
Genomic location(hg38): chr8:102329089-102345545:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0043377
MONDO name: juvenile spondyloarthropathy
Disease details: juvenile spondyloarthropathies / JSpA
Disease DO ID:
 -
Disease MeSH ID:
 -
Disease NCIt ID:
 C114347
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

peripheral blood mononuclear cells (PBMCs)
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-1225-3p, hsa-miR-1825, hsa-miR-193a-5p, hsa-miR-300, hsa-miR-485-3p, hsa-miR-548c-5p, hsa-miR-628-3p
Biological function: -
Molecular mechanism: ceRNA network (bioinformatics-predicted circRNA-miRNA-mRNA interactions)
Biological pathway or process:

ceRNA regulation (other); JAK/STAT (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0005070 was identified as downregulated and incorporated into the JSpA-related circRNA-miRNA-mRNA ceRNA network constructed from GEO microarray datasets. Its role was inferred via bioinformatics prediction rather than experimental validation.
Confidence score:

0.1768
Other information
Title:

Identifying circRNA-associated-ceRNA networks in juvenile spondyloarthropathies patients.

Journal: Pediatric rheumatology online journal
Published: 2023
PubMed ID: 37507775
Study type:

bioinformatics study
Data availability: GSE178408; GSE79481; GSE58667
Code availability: -