circRNA basic information
circBase ID: hsa_circ_0079439
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr7:11101417-11101712:+
Genomic location(hg38): chr7:11061790-11062085:+
Subcellular localization: exosome
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0001056
MONDO name: gastric cancer
Disease details: gastric cancer / GC
Disease DO ID:
 10534
Disease MeSH ID:
 -
Disease NCIt ID:
 C9331
Disease ICD11 ID:
 1397617262
Disease OMIM ID:
 613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

plasma
Cell lines:

AGS; HGC-27; KATO III; SNU-1; SGC-7901; MGC-803; BGC-823; NGECs
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: unknown
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; Bioinformatics Analysis; RT-qPCR; divergent primers PCR; Clinical Sample Validation; Cohort Study; ROC Analysis
Clinical significance:

Plasma exosomal hsa_circ_0079439 has diagnostic value for distinguishing GC (including EGC and AGC) patients from healthy donors and decreases after treatment.
Description:

Plasma exosomal hsa_circ_0079439 is upregulated in gastric cancer (including early and advanced stages) and shows strong diagnostic performance versus standard serum biomarkers. Its level decreases after treatment, supporting its use as a liquid-biopsy biomarker for GC detection and monitoring.
Confidence score:

0.636
Other information
Title:

Plasma exosomal hsa_circ_0079439 as a novel biomarker for early detection of gastric cancer.

Journal: World journal of gastroenterology
Published: 2023
PubMed ID: 37389236
Study type:

combined biological and clinical study
Data availability: The data that support the findings of this study are available from the corresponding author upon reasonable request.
Code availability: -