circRNA basic information
circBase ID: hsa_circ_0001387
Name: hsa_circ_WHSC1
Synonym: -
Host Gene: WHSC1
Genomic location(hg19): chr4:1902352-1936989:+
Genomic location(hg38): chr4:1900625-1935262:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007256
MONDO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma / HCC
Disease DO ID:
 684, 686
Disease MeSH ID:
 D006528
Disease NCIt ID:
 C3099
Disease ICD11 ID:
 1294035808
Disease OMIM ID:
 114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

tumor tissues; matched adjacent non-tumorous tissues; adjacent chronic hepatitis tissues; HCC tissues
Cell lines:

Huh-7; HepG2; SK-Hep-1; QGY-7703
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: No specific biological function was established; hsa_circ_0001387 was significantly increased in HCC tissues but was not correlated with DFS or OS.
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation; Sanger Sequencing; Actinomycin D / DRB Stability Assay; RNase R Treatment; Survival Analysis; Bioinformatics Analysis
Clinical significance:

hsa_circ_0001387 expression was not correlated with DFS or OS of HCC patients.
Description:

hsa_circ_0001387 is up-regulated in HCC tissues compared with adjacent non-tumorous tissues. The study confirmed its circular characteristics, but it was not correlated with DFS or OS and no mechanism or functional role was pursued.
Confidence score:

0.6841
Other information
Title:

Circular RNA hsa_circ_0098181 inhibits metastasis in hepatocellular carcinoma by activating the Hippo signaling pathway via interaction with eEF2.

Journal: Annals of hepatology
Published: 2023
PubMed ID: 37286166
Study type:

combined biological and clinical study
Data availability: GSE121714
Code availability: -