circRNA basic information
circBase ID: hsa_circ_0002980
Name: hsa_circ_AGK
Synonym: circRNA.9521
Host Gene: AGK
Genomic location(hg19): chr7:141336759-141349133:+
Genomic location(hg38): chr7:141636959-141649333:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007028
MONDO name: rotator cuff syndrome
Disease details: rotator cuff tendinopathy
Disease DO ID:
 -
Disease MeSH ID:
 -
Disease NCIt ID:
 -
Disease ICD11 ID:
 1471943310
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

supraspinatus tendons / rotator cuff tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: Differentially expressed circRNA potentially involved in the occurrence and development of rotator cuff tendinopathy.
Molecular mechanism: Potential involvement through parental-gene enriched pathways and predicted ceRNA network; no circRNA-specific mechanism experimentally validated.
Biological pathway or process:

cell cycle (other); NF-kappaB (other); other pathway/process (other)
Detected method:
S
Validation methods:

circRNA-seq; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

Potential therapeutic targets for rotator cuff tendinopathy.
Description:

circRNA.9521, also named hsa_circ_0002980, was identified as up-regulated in rotator cuff tendinopathy tissue. The study links differentially expressed circRNAs to potential disease mechanisms through pathway enrichment and ceRNA network analysis.
Confidence score:

0.3991
Other information
Title:

[Circular RNA expression pattern and competing endogenous RNA network involved in rotator cuff tendinopathy].

Journal: Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
Published: 2020
PubMed ID: 32410429
Study type:

bioinformatics study
Data availability: -
Code availability: -