| Expression pattern: |
UP |
| Associated gene: |
- |
| Associated microRNA: |
- |
| Biological function: |
Circ-MTO1 is upregulated in GBC tissues and plasma, is associated with clinicopathological characteristics, and serves as a potential diagnostic and prognostic biomarker; high circ-MTO1 expression predicts poor OS and PFS. |
| Molecular mechanism: |
- |
| Biological pathway or process: |
other pathway/process (other) |
| Detected method: |
Q
|
| Validation methods: |
RT-qPCR; Clinical Sample Validation; Cohort Study; Survival Analysis; ROC Analysis |
| Clinical significance: |
High circ-MTO1 expression served as an independent prognostic factor for poor OS and PFS in GBC patients, and plasma circ-MTO1 has potential early diagnostic value. |
| Description: |
This study found that circ-MTO1 is significantly upregulated in gallbladder cancer tissues and patient plasma. Its high expression is associated with adverse clinicopathological features and shorter OS and PFS, supporting circ-MTO1 as a potential diagnostic and prognostic biomarker for GBC. |
| Confidence score: |
0.4992 |