circRNA basic information
circBase ID: -
Name: hsa_circ_RSF1
Synonym: circ-RSF1
Host Gene: RSF1
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005047
MONDO name: infertility disorder
Disease details: infertility
Disease DO ID:
 5223
Disease MeSH ID:
 D007246
Disease NCIt ID:
 C3836
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

endometrial samples
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: circ-RSF1 is an infertility-associated DEcircRNA significantly upregulated after acupuncture and moxibustion; the article suggests acupuncture and moxibustion affect ER via regulation of circRNA expression.
Molecular mechanism: Not specifically defined for circ-RSF1; the study performed aggregate GO/KEGG analysis of DEcircRNA host genes.
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RT-qPCR; RNA-seq; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

Potentially related to endometrial receptivity in infertile patients treated with acupuncture and moxibustion.
Description:

circ-RSF1 was validated by RT-qPCR as significantly upregulated in endometrial samples from infertile patients treated with acupuncture and moxibustion. The study did not provide a circ-RSF1-specific regulatory axis or functional experiment beyond expression validation.
Confidence score:

0.4032
Other information
Title:

Circular RNA sequencing reveals the molecular mechanism of the effects of acupuncture and moxibustion on endometrial receptivity in patients undergoing infertility treatment.

Journal: Molecular medicine reports
Published: 2019
PubMed ID: 31257480
Study type:

combined clinical and bioinformatics study
Data availability: available from the corresponding author on reasonable request
Code availability: -