| Expression pattern: |
UP |
| Associated gene: |
BTG-2 |
| Associated microRNA: |
miR-134-5p |
| Biological function: |
promotes cell proliferation and migration; acts as an oncogene |
| Molecular mechanism: |
ceRNA mechanism; binds miR-134-5p to relieve repression of BTG-2 |
| Biological pathway or process: |
proliferation (promotes); migration (promotes); ceRNA regulation (other) |
| Detected method: |
Q
|
| Validation methods: |
RT-qPCR; Luciferase Reporter Assay; CCK8; Wound Healing Assay; Transfection; Western Blot; Bioinformatics Analysis |
| Clinical significance: |
- |
| Description: |
CircZNF609 is upregulated in glioma cell lines and promotes glioma cell proliferation and migration. It functions as a ceRNA for miR-134-5p and thereby modulates BTG-2 expression. |
| Confidence score: |
0.5554 |