circRNA basic information
circBase ID: hsa_circ_0008450
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr16:66642211-66643906:+
Genomic location(hg38): chr16:66608308-66610003:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007256
MONDO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma / HCC
Disease DO ID:
 684, 686
Disease MeSH ID:
 D006528
Disease NCIt ID:
 C3099
Disease ICD11 ID:
 1294035808
Disease OMIM ID:
 114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

HCC tissues; nontumor tissue samples; corresponding nontumourous tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

Back-Splice Junction PCR / divergent primers PCR; RNase R Treatment; circRNA-seq; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0008450 was among the top up-regulated circRNAs identified by high-throughput circRNA sequencing and was validated by RT-qPCR as significantly increased in HCC tissues compared with corresponding nontumourous tissues. No functional or mechanistic experiments were reported for this circRNA.
Confidence score:

0.5841
Other information
Title:

Hsa_circ_0103809 promotes cell proliferation and inhibits apoptosis in hepatocellular carcinoma by targeting miR-490-5p/SOX2 signaling pathway.

Journal: American journal of translational research
Published: 2018
PubMed ID: 30018710
Study type:

combined biological and clinical study
Data availability: -
Code availability: -