circRNA basic information
circBase ID: -
Name: hsa_circ_C1ORF116
Synonym: circ_C1orf116
Host Gene: C1ORF116
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005233
MONDO name: non-small cell lung carcinoma
Disease details: non-small cell lung cancer / NSCLC
Disease DO ID:
 3908
Disease MeSH ID:
 D002289
Disease NCIt ID:
 C2926
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

FFPE lung cancer tissues; FFPE tissue samples
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: BBX8
Associated microRNA: miR-518d-5p, miR-519-5p
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Others
Validation methods:

Bioinformatics Analysis
Clinical significance:

Upregulated in NSCLC FFPE tissues (including early-stage comparison figure caption)
Description:

circC1ORF116 (also written as circ_C1orf116) is up-regulated in NSCLC FFPE tissues by nCounter profiling. No NSCLC-specific functional mechanism was experimentally validated in this study; discussion cites prior evidence in cervical cancer involving miR-518d-5p/miR-519-5p and BBX8.
Confidence score:

0.0693
Other information
Title:

Digital multiplexed analysis of circular RNAs in FFPE and fresh non-small cell lung cancer specimens.

Journal: Molecular oncology
Published: 2022
PubMed ID: 35060299
Study type:

combined biological and clinical study
Data availability: The data that support the findings of this study are available from the corresponding author (carlospedraz@icloud.com) upon reasonable request.
Code availability: -