circRNA basic information
circBase ID: hsa_circ_0005303
Name: hsa_circ_SCMH1
Synonym: -
Host Gene: SCMH1
Genomic location(hg19): chr1:41651792-41660071:-
Genomic location(hg38): chr1:41186120-41194399:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0043377
MONDO name: juvenile spondyloarthropathy
Disease details: juvenile spondyloarthropathies / JSpA
Disease DO ID:
 -
Disease MeSH ID:
 -
Disease NCIt ID:
 C114347
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

peripheral blood mononuclear cells (PBMCs)
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-1225-3p, hsa-miR-1825, hsa-miR-193a-5p, hsa-miR-300, hsa-miR-485-3p, hsa-miR-548c-5p, hsa-miR-628-3p
Biological function: -
Molecular mechanism: ceRNA network (bioinformatics-predicted circRNA-miRNA-mRNA interactions)
Biological pathway or process:

ceRNA regulation (other); JAK/STAT (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0005303 was found downregulated and included in the final JSpA-related ceRNA network built from GEO microarray datasets and target-prediction databases. The study provides only computational evidence for its regulatory involvement.
Confidence score:

0.1768
Other information
Title:

Identifying circRNA-associated-ceRNA networks in juvenile spondyloarthropathies patients.

Journal: Pediatric rheumatology online journal
Published: 2023
PubMed ID: 37507775
Study type:

bioinformatics study
Data availability: GSE178408; GSE79481; GSE58667
Code availability: -