circRNA basic information
circBase ID: hsa_circ_0001944
Name: -
Synonym: circ_0001944
Host Gene: -
Genomic location(hg19): chrX:130883333-130928494:-
Genomic location(hg38): chrX:131749305-131794466:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
0007256
MONDO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma / HCC
Disease DO ID:
684, 686
Disease MeSH ID:
D006528
Disease NCIt ID:
C3099
Disease ICD11 ID:
1294035808
Disease OMIM ID:
114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

-

Cell lines:

SMMC7721/S; Huh7/S; SMMC7721; Huh7

In vivo animal model:

-

circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified

Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis

Clinical significance:

-

Description:

circ_0001944 was identified by whole transcriptome sequencing as an upregulated circRNA in both sorafenib-resistant SMMC7721/S and Huh7/S hepatocellular carcinoma cell lines compared with parental cells. No specific miRNA/mRNA interaction axis or functional mechanism was experimentally established for circ_0001944 in this study.

Confidence score:

0.1768

Other information
Title:

Deciphering the role of non-coding RNAs involved in sorafenib resistance.

Journal: Heliyon
Published: 2024
PubMed ID: 38644890
Study type:

biological research; bioinformatics study

Data availability: available from the corresponding author upon a reasonable request; https://doi.org/10.1016/j.heliyon.2024.e29374
Code availability: -