circRNA basic information
circBase ID: -
Name: hsa_circ_USP10
Synonym: hsa_circRNA_101889
Host Gene: USP10
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 -
MONDO name: -
Disease details: aging
Disease DO ID:
 -
Disease MeSH ID:
 D000375
Disease NCIt ID:
 C16269
Disease ICD11 ID:
 -
Disease OMIM ID:
 502000
Species: Human
Species details: Homo sapiens
Tissue specimen:

granulosa cells (GCs)
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-670-3p, hsa-miR-103a-2-5p
Biological function: Down-regulated in granulosa cells from advanced-age women; expression varies by gonadotropin treatment type.
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation
Clinical significance:

-
Description:

circRNA_101889 (hsa_circRNA_101889, from USP10) is down-regulated in granulosa cells from advanced-age women compared with young women. Its expression is affected by gonadotropin treatment type, and the study did not establish a specific mechanistic pathway or clinical predictive utility for this circRNA.
Confidence score:

0.3588
Other information
Title:

Circular RNA expression profiling of human granulosa cells during maternal aging reveals novel transcripts associated with assisted reproductive technology outcomes.

Journal: PloS one
Published: 2017
PubMed ID: 28644873
Study type:

combined biological and clinical study
Data availability: GSE97193
Code availability: -