circRNA basic information
circBase ID: hsa_circ_0000567
Name: hsa_circ_SETD3
Synonym: circSETD3
Host Gene: SETD3
Genomic location(hg19): chr14:99924615-99932150:-
Genomic location(hg38): chr14:99458278-99465813:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0008170
MONDO name: ovarian cancer
Disease details: ovarian cancer / OC
Disease DO ID:
 2394
Disease MeSH ID:
 D010051
Disease NCIt ID:
 C7431
Disease ICD11 ID:
 685124533
Disease OMIM ID:
 167000
Species: Human
Species details: Homo sapiens
Tissue specimen:

epithelial ovarian cancer tissues; normal ovarian tissues
Cell lines:

A2780
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

Back-Splice Junction PCR / divergent primers PCR; RNase R Treatment; Sanger Sequencing; RT-qPCR; RNA-seq; Clinical Sample Validation
Clinical significance:

-
Description:

circSETD3 was identified by RNA sequencing and validated by qRT-PCR as significantly down-regulated in epithelial ovarian cancer tissues compared with normal ovarian tissues. The study confirmed its circular structure, but did not experimentally investigate its biological function or molecular mechanism.
Confidence score:

0.5909
Other information
Title:

Comprehensive circular RNA expression profiles and the tumor-suppressive function of circHIPK3 in ovarian cancer.

Journal: The international journal of biochemistry & cell biology
Published: 2019
PubMed ID: 31026505
Study type:

combined biological and clinical study
Data availability: Supplementary files
Code availability: -