| Expression pattern: |
UN |
| Associated gene: |
- |
| Associated microRNA: |
- |
| Biological function: |
supports prostate cancer cell proliferation; knockdown and overexpression phenotypes were evaluated |
| Molecular mechanism: |
knockdown and overexpression produced reciprocal transcriptomic effects, suggesting a circRNA-specific functional program not caused by off-target effects |
| Biological pathway or process: |
proliferation (promotes); other pathway/process (other) |
| Detected method: |
Q
S
|
| Validation methods: |
Back-Splice Junction PCR / divergent primers PCR; RNase R Treatment; Sanger Sequencing; RT-qPCR; RNA-seq; Nuclear-Cytoplasmic Fractionation; Transfection; Bioinformatics Analysis |
| Clinical significance: |
- |
| Description: |
circSTAU2 was one of the functionally evaluated essential circRNAs in prostate cancer cell lines. Knockdown and overexpression experiments, including RNA-seq-based transcriptomic analysis, suggested circSTAU2 contributes to proliferation-related phenotypes independently of off-target effects. |
| Confidence score: |
0.6149 |