circRNA basic information
circBase ID: hsa_circ_0006038
Name: hsa_circ_STXBP6
Synonym: circ_0006038
Host Gene: STXBP6
Genomic location(hg19): chr14:25443870-25479846:-
Genomic location(hg38): chr14:24974664-25010640:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0002974
MONDO name: cervical cancer
Disease details: cervical cancer / CC
Disease DO ID:
 4362
Disease MeSH ID:
 -
Disease NCIt ID:
 C9311
Disease ICD11 ID:
 1256072522
Disease OMIM ID:
 603956
Species: Human
Species details: Homo sapiens
Tissue specimen:

formalin-fixed paraffin-embedded cervical tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: Biomarker candidate distinguishing precancerous from cancerous cervical tissues.
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
S
Validation methods:

circRNA-seq; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

Candidate circRNA for distinguishing precancerous from cancerous cervical tissue in screening context.
Description:

circ_0006038 (STXBP6-associated) is the top upregulated circRNA in precancerous versus cancerous cervical tissue comparison, indicating potential utility for stage discrimination. No mechanistic or functional validation was performed.
Confidence score:

0.3991
Other information
Title:

Novel circRNA signatures in cervical cancer: implications for early detection and screening.

Journal: Biomarkers in medicine
Published: 2026
PubMed ID: 41715885
Study type:

combined biological and clinical study
Data availability: GSE102686; GSE107472
Code availability: -