circRNA basic information
circBase ID: -
Name: hsa_circ_Foxo3
Synonym: circ-Foxo3
Host Gene: Foxo3
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0006512
MONDO name: estrogen-receptor positive breast cancer
Disease details: ER-positive breast cancer
Disease DO ID:
 0060075
Disease MeSH ID:
 -
Disease NCIt ID:
 -
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

BC samples
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: Tumor suppressive circRNA detected as downregulated in breast cancer samples by microarray; no study-specific functional experiments were reported for circ-Foxo3.
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
M
Validation methods:

Microarray
Clinical significance:

-
Description:

circ-Foxo3 was reported by the authors as a tumor-related circRNA detected by their microarray data and downregulated in breast cancer samples. It was not validated by qRT-PCR in this paper and no study-specific mechanism was presented.
Confidence score:

0.1155
Other information
Title:

Identification and integrated analysis of key differentially expressed circular RNAs in ER-positive subtype breast cancer.

Journal: Epigenomics
Published: 2019
PubMed ID: 30417652
Study type:

combined bioinformatics and clinical study
Data availability: Supplementary Table 1; www.futuremedicine.com/doi/suppl/10.2217/epi-2018-0147
Code availability: -