circRNA basic information
circBase ID: -
Name: hsa_circ_SPECC1
Synonym: hsa-circ-000013
Host Gene: SPECC1
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0008170
MONDO name: ovarian cancer
Disease details: ovarian cancer / OC
Disease DO ID:
 2394
Disease MeSH ID:
 D010051
Disease NCIt ID:
 C7431
Disease ICD11 ID:
 685124533
Disease OMIM ID:
 167000
Species: Human
Species details: Homo sapiens
Tissue specimen:

OC tumor tissues; pericarcinous tissues; cancer tissue; pericarcinous tissue
Cell lines:

IOSE80; ES-2; SKOV3; Caov-3; OV-1063
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: Up-regulated in OC tumor tissues; no direct functional assays were performed for this circRNA.
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
Validation methods:

RT-qPCR; Clinical Sample Validation
Clinical significance:

-
Description:

SPECC1-has-circ-000013 was evaluated as one of three circRNAs in ovarian cancer. The study reports significantly higher SPECC1-has-circ-000013 expression in OC tumor tissues than in matched pericarcinous tissues by RT-PCR, but it does not report circRNA-specific functional or mechanistic validation for this circRNA.
Confidence score:

0.2995
Other information
Title:

Upregulation of Circular RNA VPS13C-has-circ-001567 Promotes Ovarian Cancer Cell Proliferation and Invasion.

Journal: Cancer biotherapy & radiopharmaceuticals
Published: 2019
PubMed ID: 30376358
Study type:

clinical study
Data availability: -
Code availability: -