circRNA basic information
circBase ID: hsa_circ_0004058
Name: hsa_circ_ZNF292
Synonym: circZNF292
Host Gene: ZNF292
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0002602
MONDO name: central nervous system disorder
Disease details: oxidative stress
Disease DO ID:
 331
Disease MeSH ID:
 D002493
Disease NCIt ID:
 C2934
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

SH-SY5Y
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: C11orf88
Associated microRNA: miR-222-3p
Biological function: hub circRNA in the PD-OS ceRNA network, potentially regulating mRNAs via miRNA sponging
Molecular mechanism: ceRNA (circRNA-miRNA-mRNA) network via miRNA sponging
Biological pathway or process:

ceRNA regulation (other)
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

-
Description:

circZNF292 is a key hub circRNA in the PD-OS ceRNA network in SH-SY5Y cells, predicted to sponge miR-222-3p and be linked to regulation of the mRNA C11orf88 within circRNA-miRNA-mRNA axes.
Confidence score:

0.1768
Other information
Title:

Oxidative Stress-Associated Alteration of circRNA and Their ceRNA Network in Differentiating Neuroblasts.

Journal: International journal of molecular sciences
Published: 2024
PubMed ID: 39596524
Study type:

biological research
Data availability: GSE161860; GSE182627
Code availability: -