circRNA basic information
circBase ID: -
Name: hsa_circ_FAM13B
Synonym: hsa-FAM13B_0019
Host Gene: FAM13B
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0012511
MONDO name: preterm premature rupture of the membranes
Disease details: Preterm birth
Disease DO ID:
 0111144
Disease MeSH ID:
 C563032
Disease NCIt ID:
 C92862
Disease ICD11 ID:
 -
Disease OMIM ID:
 610504
Species: Human
Species details: Homo sapiens
Tissue specimen:

peripheral blood
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DS
Associated gene: -
Associated microRNA: -
Biological function: Potential biomarker for PTB diagnosis/prediction.
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
S
M
Validation methods:

RNA-seq; Microarray; Clinical Sample Validation; ROC Analysis; Bioinformatics Analysis
Clinical significance:

Strong diagnostic performance for PTB (AUC = 1.000) and stable abnormal expression supported by microarray validation.
Description:

hsa-FAM13B_0019 is reported as a stable, differentially expressed circRNA in PTB peripheral blood and is highlighted as an optimal diagnostic biomarker candidate. ROC analysis reports very high discrimination ability (AUC = 1.000).
Confidence score:

0.5047
Other information
Title:

Identification and Characterization of Circular RNA as a Novel Regulator and Biomarker in Preterm Birth.

Journal: Frontiers in bioengineering and biotechnology
Published: 2020
PubMed ID: 33392159
Study type:

combined biological and clinical study
Data availability: SRP107901; SRP144363; https://www.frontiersin.org/articles/10.3389/fbioe.2020.566984/full#supplementary-material
Code availability: -