circRNA basic information
circBase ID: -
Name: hsa_circ_UBA2
Synonym: hsa_circRNA_102526
Host Gene: UBA2
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0018881
MONDO name: myelodysplastic syndrome
Disease details: myelodysplastic syndrome
Disease DO ID:
 0050908
Disease MeSH ID:
 -
Disease NCIt ID:
 C3247
Disease ICD11 ID:
 -
Disease OMIM ID:
 614286
Species: Human
Species details: Homo sapiens
Tissue specimen:

bone marrow / BM; PBMCs; peripheral blood / PB
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; divergent primers PCR; Sanger Sequencing; Back-Splice Junction PCR / divergent primers PCR; Clinical Sample Validation; ROC Analysis
Clinical significance:

Potential diagnostic biomarker for MDS (ROC AUC 0.7283). Not reported as significantly associated with overall survival.
Description:

hsa_circRNA_102526 is down-regulated in MDS bone marrow and was RT-qPCR-validated. It has potential diagnostic value by ROC analysis, but no significant overall survival association was reported.
Confidence score:

0.6605
Other information
Title:

Identification of circular RNAs as novel biomarkers and potentially functional competing endogenous RNA network for myelodysplastic syndrome patients.

Journal: Cancer science
Published: 2021
PubMed ID: 33560542
Study type:

combined biological and clinical study
Data availability: -
Code availability: -