circRNA basic information
circBase ID: hsa_circ_0067934
Name: hsa_circ_PRKCI
Synonym: -
Host Gene: PRKCI
Genomic location(hg19): chr3:170013698-170015181:+
Genomic location(hg38): chr3:170295910-170297393:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
0008903
MONDO name: lung cancer
Disease details: lung cancer
Disease DO ID:
1324
Disease MeSH ID:
-
Disease NCIt ID:
C7377
Disease ICD11 ID:
-
Disease OMIM ID:
211980
Species: Human
Species details: Homo sapiens
Tissue specimen:

-

Cell lines:

A549

In vivo animal model:

-

circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: Completely inhibited by pemetrexed treatment in A549 cells.
Molecular mechanism: Not specified.
Biological pathway or process:

not specified

Detected method:
Q
Validation methods:

divergent primers PCR; RT-qPCR

Clinical significance:

-

Description:

hsa_circ_0067934 is reported to be completely suppressed by pemetrexed in A549 lung cancer cells, indicating a strong treatment-associated downregulation (loss of detectable expression).

Confidence score:

0.279

Other information
Title:

Identification of Circular RNAs as Biomarker Candidates in Lung Cancer Treatment.

Journal: Asian Pacific journal of cancer prevention : APJCP
Published: 2024
PubMed ID: 38918678
Study type:

biological research

Data availability: -
Code availability: -