circRNA basic information
circBase ID: -
Name: -
Synonym: chr5:160757890-160763776-
Host Gene: -
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005075
MONDO name: thyroid gland papillary carcinoma
Disease details: papillary thyroid carcinoma / PTC
Disease DO ID:
 3969
Disease MeSH ID:
 -
Disease NCIt ID:
 C4035
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

PTC tissues; paired normal thyroid tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: mRNAs
Associated microRNA: hsa-miR-3154, hsa-miR-2392, hsa-miR-6833-5p, hsa-miR-7114-5p, hsa-miR-5004-5p
Biological function: potential diagnostic biomarker for PTC
Molecular mechanism: predicted ceRNA mechanism by binding miRNAs and regulating mRNAs
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
S
Validation methods:

circRNA-seq; RT-qPCR; Clinical Sample Validation; ROC Analysis; Bioinformatics Analysis; RNA-seq
Clinical significance:

promising biomarker for identifying PTC
Description:

chr5:160757890-160763776- was up-regulated in PTC tissues and validated by qRT-PCR. It was evaluated as a potential diagnostic biomarker and was predicted to participate in a circRNA-miRNA-mRNA ceRNA network.
Confidence score:

0.5963
Other information
Title:

The Landscape of Circular RNA Expression Profiles in Papillary Thyroid Carcinoma Based on RNA Sequencing.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Published: 2018
PubMed ID: 29847813
Study type:

combined bioinformatics and clinical study
Data availability: -
Code availability: -