circRNA basic information
circBase ID: -
Name: -
Synonym: hsa_circ_102032
Host Gene: -
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
0007256
MONDO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma / HCC
Disease DO ID:
684, 686
Disease MeSH ID:
D006528
Disease NCIt ID:
C3099
Disease ICD11 ID:
1294035808
Disease OMIM ID:
114550
Species: Human
Species details: Homo sapiens
Tissue specimen:

peripheral blood; plasma

Cell lines:

-

In vivo animal model:

-

circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: Potential peripheral blood diagnostic biomarker associated with PHC; decreasing after liver transplantation may reflect removal of PHC-related circRNA.
Molecular mechanism: -
Biological pathway or process:

not specified

Detected method:
Q
M
Validation methods:

RNase R Treatment; RT-qPCR; Microarray; Clinical Sample Validation

Clinical significance:

May have relationship with PHC and may serve as a novel tool for clinical diagnosis of PHC.

Description:

hsa_circ_102032 was significantly up-regulated in pre-transplantation peripheral blood from PHC patients compared with normal controls and decreased after liver transplantation. The study suggests it may be associated with PHC and may have potential diagnostic biomarker value.

Confidence score:

0.4773

Other information
Title:

The differentially expressed circular ribonucleic acids of primary hepatic carcinoma following liver transplantation as new diagnostic biomarkers for primary hepatic carcinoma.

Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Published: 2018
PubMed ID: 29609527
Study type:

combined clinical and bioinformatics study

Data availability: -
Code availability: -