circRNA basic information
circBase ID: hsa_circ_0066830
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): chr3:113503542-113505230:+
Genomic location(hg38): chr3:113784695-113786383:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0008383
MONDO name: rheumatoid arthritis
Disease details: rheumatoid arthritis / RA
Disease DO ID:
 7148
Disease MeSH ID:
 D001172
Disease NCIt ID:
 C2884
Disease ICD11 ID:
 576319925
Disease OMIM ID:
 180300
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

MH7A
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DS
Associated gene: -
Associated microRNA: hsa-miR-1208, hsa-miR-548m, hsa-miR-548c-3p, hsa-miR-1253, hsa-miR-767-5p
Biological function: -
Molecular mechanism: Identified as a differentially expressed circRNA after DGNTG treatment and included in a representative circRNA-miRNA-mRNA ceRNA network.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0066830 was identified as a DGNTG-responsive circRNA in MH7A rheumatoid arthritis model cells (supported by microarray and RT-qPCR), and was included in the representative ceRNA network constructed by the authors; direction of change was not stated in the provided text.
Confidence score:

0.4032
Other information
Title:

Danggui Niantong granules in the treatment of rheumatoid arthritis - a mechanistic approach using ceRNA networks.

Journal: Frontiers in pharmacology
Published: 2026
PubMed ID: 41727546
Study type:

biological research
Data availability: GSE318151
Code availability: -