circRNA basic information
circBase ID: hsa_circ_0083466
Name: hsa_circ_ASAH1
Synonym: -
Host Gene: ASAH1
Genomic location(hg19): chr8:17916343-17927387:-
Genomic location(hg38): chr8:18058834-18069878:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
0008383
MONDO name: rheumatoid arthritis
Disease details: rheumatoid arthritis / RA
Disease DO ID:
7148
Disease MeSH ID:
D001172
Disease NCIt ID:
C2884
Disease ICD11 ID:
576319925
Disease OMIM ID:
180300
Species: Human
Species details: Homo sapiens
Tissue specimen:

-

Cell lines:

MH7A

In vivo animal model:

-

circRNA-disease information
Expression pattern:
UN
Associated gene: ASAH1
Associated microRNA: hsa-miR-1208, hsa-miR-548m, hsa-miR-548c-3p, hsa-miR-1253, hsa-miR-767-5p
Biological function: -
Molecular mechanism: Representative circRNA-miRNA-mRNA (ceRNA) network component; circRNA positively correlated with its host mRNA (moderate correlation).
Biological pathway or process:

ceRNA regulation (other)

Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis

Clinical significance:

-

Description:

hsa_circ_0083466 was included in the representative circRNA-miRNA-mRNA ceRNA network constructed in DGNTG-treated MH7A RA model cells, and showed a moderate correlation with its host gene ASAH1.

Confidence score:

0.1768

Other information
Title:

Danggui Niantong granules in the treatment of rheumatoid arthritis - a mechanistic approach using ceRNA networks.

Journal: Frontiers in pharmacology
Published: 2026
PubMed ID: 41727546
Study type:

biological research

Data availability: GSE318151
Code availability: -