circRNA basic information
circBase ID: -
Name: hsa_circ_CYP24A1
Synonym: circCYP24A1
Host Gene: CYP24A1
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005061
MONDO name: lung adenocarcinoma
Disease details: lung adenocarcinoma / LUAD
Disease DO ID:
 3910
Disease MeSH ID:
 C538231
Disease NCIt ID:
 C3512
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

NCIH1944; NCIH2291; NCIH23
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: RBM10
Associated microRNA: -
Biological function: -
Molecular mechanism: Indirect RBM10-dependent regulation suggested; direct RBM10 binding not confirmed due to lack of PAR-CLIP reads at flanking sites.
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR
Clinical significance:

-
Description:

circCYP24A1 is an RBM10-dependent circRNA identified by RNA-seq and confirmed by RT-qPCR in LUAD cell models, but direct RBM10 binding to its flanking sites was not supported by PAR-CLIP, suggesting indirect regulation.
Confidence score:

0.1904
Other information
Title:

RBM10 modulation of circRNA biogenesis contributes to its tumor suppressor role in lung adenocarcinoma.

Journal: Biomarker research
Published: 2026
PubMed ID: 41673707
Study type:

biological research
Data availability: GSE000000; PXD071457; 10.1186/s40364-026-00891-6
Code availability: -