circRNA basic information
circBase ID: hsa_circ_0008450
Name: hsa_circ_CMTM3
Synonym: circCMTM3
Host Gene: -
Genomic location(hg19): chr16:66642211-66643906:+
Genomic location(hg38): chr16:66608308-66610003:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0015469
MONDO name: craniosynostosis
Disease details: craniosynostosis
Disease DO ID:
 2340
Disease MeSH ID:
 D003398
Disease NCIt ID:
 C84655
Disease ICD11 ID:
 458033798
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

cranial suture tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; Clinical Sample Validation
Clinical significance:

-
Description:

circCMTM3 (hsa_circ_0008450) was identified as up-regulated in craniosynostosis cranial suture tissues by microarray and validated by RT-qPCR. The paper did not further investigate its function or mechanism.
Confidence score:

0.3588
Other information
Title:

MSC Membrane-Coated circPROSC-siRNA Nanoparticles for Ameliorating Craniosynostosis by Inhibiting Premature Suture Ossification.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: 2026
PubMed ID: 41178597
Study type:

combined biological and clinical study
Data availability: The data that support the findings of this study are available from the corresponding author upon reasonable request.
Code availability: -