circRNA basic information
circBase ID: hsa_circ_0000471
Name: hsa_circ_N4BP2L2
Synonym: circN4BP2L2
Host Gene: -
Genomic location(hg19): chr13:33091993-33101669:-
Genomic location(hg38): chr13:32517856-32527532:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005045
MONDO name: hypertrophic cardiomyopathy
Disease details: cardiac hypertrophy
Disease DO ID:
 11984
Disease MeSH ID:
 D002312
Disease NCIt ID:
 C34449
Disease ICD11 ID:
 1830681485
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

ventricular tissue
Cell lines:

-
In vivo animal model:

other disease animal model
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; In Vivo Animal Model
Clinical significance:

-
Description:

circN4BP2L2 was identified by ventricular circRNA profiling and validated by RT-qPCR as significantly down-regulated in TAC-induced hypertrophic mouse hearts; no functional/mechanistic experiments were reported for this circRNA.
Confidence score:

0.3213
Other information
Title:

A circular RNA derived from the ryanodine receptor 2 locus controls cardiac hypertrophy and calcium handling.

Journal: Cellular and molecular life sciences : CMLS
Published: 2025
PubMed ID: 41117932
Study type:

biological research
Data availability: All data will be shared upon reasonable request to the corresponding author.
Code availability: -