circRNA basic information
circBase ID: -
Name: hsa_circ_MSR1
Synonym: hsa_circRNA_407041 / hsa-circRNA-407041
Host Gene: MSR1
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007254
MONDO name: breast cancer
Disease details: breast cancer
Disease DO ID:
 1612
Disease MeSH ID:
 -
Disease NCIt ID:
 C9335
Disease ICD11 ID:
 1047754165
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

breast cancer tissues; adjacent non-tumor breast tissues; matched-normal tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-200b-3p, has-miR-200c-3p, hsa-miR-425-5p, hsa-miR-301a-3p, hsa-miR-7-5p
Biological function: -
Molecular mechanism: Predicted ceRNA interaction (circRNA binds miRNAs in CERNOMA network).
Biological pathway or process:

ceRNA regulation (other); MAPK (other); PI3K/AKT (other); Wnt/beta-catenin (other); other pathway/process (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circRNA_407041 is down-regulated in breast cancer and is predicted (via circFunBase-based network analysis) to bind multiple oncogenic/BC-related miRNAs, supporting a putative ceRNA role within the CERNOMA network.
Confidence score:

0.1768
Other information
Title:

Circular RNA mediated gene regulation in human breast cancer: A bioinformatics analysis.

Journal: PloS one
Published: 2023
PubMed ID: 37494404
Study type:

bioinformatics study
Data availability: GSE182471; TCGA (February 2022, breast invasive carcinoma (brca))
Code availability: -