circRNA basic information
circBase ID: hsa_circ_0028190
Name: hsa_circ_ANAPC7
Synonym: circANAPC7
Host Gene: ANAPC7
Genomic location(hg19): chr12:110820647-110834257:-
Genomic location(hg38): chr12:110382842-110396452:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0001056
MONDO name: gastric cancer
Disease details: gastric cancer
Disease DO ID:
 10534
Disease MeSH ID:
 -
Disease NCIt ID:
 C9331
Disease ICD11 ID:
 1397617262
Disease OMIM ID:
 613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

GC tissue; normal gastric mucosa; matched paracancerous tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: CDK6, TGFBR1
Associated microRNA: hsa-mir-4291, hsa-mir-140-5p
Biological function: unknown
Molecular mechanism: Predicted ceRNA mechanism via miRNA sponging (hsa-mir-4291 and hsa-mir-140-5p) to regulate CDK6 and TGFBR1 in a circRNA-miRNA-mRNA network.
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0028190 (circANAPC7) is identified as a down-regulated circRNA in gastric cancer tissues by GEO microarray integration. The study predicts two ceRNA axes involving this circRNA: hsa_circ_0028190-hsa-mir-4291-CDK6 and hsa_circ_0028190-hsa-mir-140-5p-TGFBR1, without experimental validation.
Confidence score:

0.1768
Other information
Title:

Identification of Potentially Functional CircRNA-miRNA-mRNA Regulatory Network in Gastric Carcinoma using Bioinformatics Analysis.

Journal: Medical science monitor : international medical journal of experimental and clinical research
Published: 2019
PubMed ID: 31747387
Study type:

bioinformatics study
Data availability: GSE78092; GSE89143; GSE93415; GSE54129; TCGA
Code availability: -