circRNA basic information
circBase ID: -
Name: hsa_circ_COL1A1
Synonym: circRNA.3431
Host Gene: COL1A1
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0007028
MONDO name: rotator cuff syndrome
Disease details: rotator cuff tendinopathy
Disease DO ID:
 -
Disease MeSH ID:
 -
Disease NCIt ID:
 -
Disease ICD11 ID:
 1471943310
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

supraspinatus tendons / rotator cuff tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: Differentially expressed circRNA potentially involved in the occurrence and development of rotator cuff tendinopathy.
Molecular mechanism: Potential involvement through parental-gene enriched pathways and predicted ceRNA network; no circRNA-specific mechanism experimentally validated.
Biological pathway or process:

cell cycle (other); NF-kappaB (other); other pathway/process (other)
Detected method:
S
Validation methods:

circRNA-seq; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

Potential therapeutic targets for rotator cuff tendinopathy.
Description:

circRNA.3431 was identified as one of the most up-regulated circRNAs in rotator cuff tendinopathy tissue by circRNA sequencing. Its host gene is COL1A1, and the study suggests that differentially expressed circRNAs may provide potential diagnostic or therapeutic targets.
Confidence score:

0.3991
Other information
Title:

[Circular RNA expression pattern and competing endogenous RNA network involved in rotator cuff tendinopathy].

Journal: Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
Published: 2020
PubMed ID: 32410429
Study type:

bioinformatics study
Data availability: -
Code availability: -