circRNA basic information
circBase ID: hsa_circ_0000519
Name: hsa_circ_RPPH1
Synonym: -
Host Gene: RPPH1
Genomic location(hg19): chr14:20811436-20811534:-
Genomic location(hg38): chr14:20343277-20343375:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005061
MONDO name: lung adenocarcinoma
Disease details: lung adenocarcinoma / LUAD
Disease DO ID:
 3910
Disease MeSH ID:
 C538231
Disease NCIt ID:
 C3512
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

LUAD tissues; normal tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-328-3p
Biological function: Not specified (only included in initial ceRNA network construction).
Molecular mechanism: Potential circRNA-miRNA interaction within a ceRNA network (no downstream target validated).
Biological pathway or process:

not specified
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0000519 was identified as an up-regulated differentially expressed circRNA in LUAD microarray datasets and was included in the constructed ceRNA network as a predicted binder of hsa-miR-328-3p. No experimental validation or downstream functional mechanism was reported for this circRNA in this study.
Confidence score:

0.1768
Other information
Title:

Integrated analysis reveals key circRNA-mediated regulatory axes related to prognosis and immune infiltration in lung adenocarcinoma.

Journal: BMC medical genomics
Published: 2025
PubMed ID: 40640792
Study type:

bioinformatics study
Data availability: GSE101586; GSE101684; TCGA-LUAD; GSE68465
Code availability: -