circRNA basic information
circBase ID: hsa_circ_0000467
Name: hsa_circ_SKA3
Synonym: circSKA3
Host Gene: SKA3
Genomic location(hg19): chr13:21742126-21742538:-
Genomic location(hg38): chr13:21167987-21168399:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0008170
MONDO name: ovarian cancer
Disease details: ovarian cancer / OC
Disease DO ID:
 2394
Disease MeSH ID:
 D010051
Disease NCIt ID:
 C7431
Disease ICD11 ID:
 685124533
Disease OMIM ID:
 167000
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

A2780; SKOV3
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR
Clinical significance:

-
Description:

circSKA3 was identified by RNA-seq as one of three circRNAs reduced after erastin treatment and its downregulation was confirmed by qRT-PCR in ovarian cancer cells, suggesting a potential association with ferroptosis induction.
Confidence score:

0.1904
Other information
Title:

CircASH1L inhibits ferroptosis and enhances cisplatin resistance by sponging miR-515-5p to regulate cell cycle-related CDCA7/RRM2 in ovarian cancer cells.

Journal: Frontiers in pharmacology
Published: 2025
PubMed ID: 40630134
Study type:

biological research
Data availability: -
Code availability: -