circRNA basic information
circBase ID: mmu_circ_0001797
Name: mmu_circ_Zfp609
Synonym: circZfp609circZNF609
Host Gene: Zfp609/ZNF609
Genomic location(hg19): chr15:64791491-64792365:+
Genomic location(hg38): chr15:64499292-64500166:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0004976
MONDO name: amyotrophic lateral sclerosis
Disease details: amyotrophic lateral sclerosis / ALS
Disease DO ID:
 332
Disease MeSH ID:
 D000690
Disease NCIt ID:
 C34373
Disease ICD11 ID:
 1982355687
Disease OMIM ID:
 -
Species: Mouse
Species details: Mus musculus
Tissue specimen:

spinal cord; quadriceps
Cell lines:

-
In vivo animal model:

genetically engineered animal model
circRNA-disease information
Expression pattern:
DS
Associated gene: Zfp609/ZNF609
Associated microRNA: -
Biological function: -
Molecular mechanism: circRNA/host-gene expression correlation (spinal cord only)
Biological pathway or process:

not specified
Detected method:
Q
Validation methods:

RT-qPCR
Clinical significance:

-
Description:

circZfp609/circZNF609 is among the circRNAs profiled in ALS tissues and shows a significant positive correlation with its host gene expression specifically in spinal cord, consistent with coordinated deregulation in ALS.
Confidence score:

0.1155
Other information
Title:

Circular RNA expression in ALS is progressively deregulated and tissue-dependent.

Journal: BMC genomics
Published: 2025
PubMed ID: 40596818
Study type:

biological research
Data availability: -
Code availability: -