circRNA basic information
circBase ID: -
Name: hsa_circ_CORO1C
Synonym: circCORO1C
Host Gene: CORO1C+K8
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005233
MONDO name: non-small cell lung carcinoma
Disease details: non-small cell lung cancer / NSCLC
Disease DO ID:
 3908
Disease MeSH ID:
 D002289
Disease NCIt ID:
 C2926
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

FFPE lung cancer tissues; FFPE tissue samples
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Others
Validation methods:

Bioinformatics Analysis; ROC Analysis
Clinical significance:

Included in 8-circRNA signature for NSCLC vs controls and 4-circRNA signature for early-stage NSCLC vs controls; negatively correlated with smoking status
Description:

circCORO1C is part of ML-derived circRNA signatures that classify NSCLC (including early-stage cases) versus controls using nCounter data, and its expression is reported to correlate with smoking status; however, its direction of differential expression in NSCLC versus controls is not explicitly stated in the provided text.
Confidence score:

0.2629
Other information
Title:

Digital multiplexed analysis of circular RNAs in FFPE and fresh non-small cell lung cancer specimens.

Journal: Molecular oncology
Published: 2022
PubMed ID: 35060299
Study type:

combined biological and clinical study
Data availability: The data that support the findings of this study are available from the corresponding author (carlospedraz@icloud.com) upon reasonable request.
Code availability: -