| Expression pattern: |
DN |
| Associated gene: |
mTOR |
| Associated microRNA: |
- |
| Biological function: |
unknown |
| Molecular mechanism: |
Association with mTOR/autophagy marker reported; no direct mechanistic experiments in this study |
| Biological pathway or process: |
autophagy (other); other pathway/process (other) |
| Detected method: |
Q
|
| Validation methods: |
RT-qPCR; ELISA; Clinical Sample Validation |
| Clinical significance: |
Altered in CKD and correlated with Creatinine, GFR and albumin/Creatinine (A/C) ratio; suggested as biomarker for prognosis/diagnosis/monitoring. |
| Description: |
Circ-SLC8A1 is down-regulated in CKD patient serum. The study reports its altered expression together with mTOR/autophagy marker changes and correlations with renal function indices, supporting potential biomarker relevance in CKD. |
| Confidence score: |
0.4128 |