| Expression pattern: |
UP |
| Associated gene: |
- |
| Associated microRNA: |
hsa-miR-1182, hsa-miR-1289 |
| Biological function: |
potential regulatory roles in GBM pathogenesis |
| Molecular mechanism: |
predicted miRNA binding (ceRNA network construction) |
| Biological pathway or process: |
ceRNA regulation (other); apoptosis (other); cell cycle (other); MAPK (other); PI3K/AKT (other) |
| Detected method: |
S
M
|
| Validation methods: |
RNA-seq; Microarray; Bioinformatics Analysis |
| Clinical significance: |
potential regulatory roles in GBM pathogenesis; may facilitate the identification of novel biomarkers |
| Description: |
hsa_circ_0001730 is predicted to be up-regulated in GBM brain tissues and included in a constructed circRNA-miRNA network, with predicted binding to hsa-miR-1182 and hsa-miR-1289, suggesting a potential regulatory role in GBM. |
| Confidence score: |
0.2465 |