circRNA basic information
circBase ID: hsa_circ_0000517
Name: -
Synonym: -
Host Gene: -
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0004781
MONDO name: acute myocardial infarction
Disease details: acute myocardial infarction / AMI
Disease DO ID:
 9408
Disease MeSH ID:
 -
Disease NCIt ID:
 C35204
Disease ICD11 ID:
 1334938734
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

blood
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: DYNLL1
Associated microRNA: hsa-miR-330-5p
Biological function: -
Molecular mechanism: Predicted ceRNA network involvement with hsa-miR-330-5p and DYNLL1
Biological pathway or process:

ceRNA regulation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa-circ-0000517 was predicted (microarray + StarBase-based filtering) to participate in an AMI ceRNA axis by interacting with hsa-miR-330-5p and linking to DYNLL1. The paper provides no experimental validation for this circRNA.
Confidence score:

0.1768
Other information
Title:

Identification and validation of key genes associated with cell senescence in acute myocardial infarction.

Journal: Frontiers in cardiovascular medicine
Published: 2025
PubMed ID: 40046960
Study type:

combined biological and clinical study
Data availability: GSE160717; GSE31568; GSE60993; GSE66360
Code availability: -