| Expression pattern: |
UP |
| Associated gene: |
- |
| Associated microRNA: |
- |
| Biological function: |
Potential biomarker for prognosis, diagnosis, and treatment of CCM; significantly downregulated after liver transplantation and therefore relatively higher before transplantation in CCM patients. |
| Molecular mechanism: |
Not experimentally defined for circ-ASAP1; the study mainly identified differential expression by RNA sequencing and qRT-PCR. |
| Biological pathway or process: |
not specified |
| Detected method: |
Q
S
|
| Validation methods: |
RT-qPCR; RNA-seq; Clinical Sample Validation; Bioinformatics Analysis |
| Clinical significance: |
Potential biomarker for prognosis, diagnosis, and treatment of CCM. |
| Description: |
circ-ASAP1 was significantly downregulated after liver transplantation compared with before transplantation in CCM patients, consistent with RNA sequencing and qRT-PCR. The authors propose that circ-ASAP1 may be an important circRNA related to CCM occurrence/development and a potential biomarker for prognosis, diagnosis, and treatment. |
| Confidence score: |
0.4032 |