circRNA basic information
circBase ID: -
Name: hsa_circ_EPB41L5
Synonym: circEPB41L5 / circEBP41L5
Host Gene: EPB41L5
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0018177
MONDO name: glioblastoma
Disease details: glioblastoma / GBM
Disease DO ID:
 3068
Disease MeSH ID:
 D005909
Disease NCIt ID:
 C3058
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

tumor tissues; healthy brain
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; RNase R Treatment
Clinical significance:

-
Description:

circEPB41L5/circEBP41L5 is strongly down-regulated in primary GBM compared with healthy brain and shows a notable discrepancy between circular and linear transcript levels; this study did not functionally characterize it beyond expression/circularity validation.
Confidence score:

0.3401
Other information
Title:

Transcriptome-wide analysis of circRNA and RBP profiles and their molecular relevance for GBM.

Journal: Molecular oncology
Published: 2025
PubMed ID: 40008750
Study type:

combined biological and clinical study
Data availability: GSE196695
Code availability: https://github.com/MSajek/GBM_circs