circRNA basic information
circBase ID: hsa_circ_0000722
Name: hsa_circ_GSE1
Synonym: -
Host Gene: GSE1
Genomic location(hg19): chr16:85667519-85667738:+
Genomic location(hg38): chr16:85633913-85634132:+
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0011122
MONDO name: obesity disorder
Disease details: obesity
Disease DO ID:
 9970
Disease MeSH ID:
 -
Disease NCIt ID:
 C3283
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

greater omentum adipose tissue / omentum adipose tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: G6PD
Associated microRNA: hsa-miR-326_R+1
Biological function: Potential regulatory role in obesity via a ceRNA network affecting metabolic genes (including G6PD).
Molecular mechanism: ceRNA regulatory network (circRNA targets miRNA that targets mRNA).
Biological pathway or process:

ceRNA regulation (other); lipid metabolism (other)
Detected method:
Q
S
Validation methods:

RNA-seq; RT-qPCR; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

-
Description:

hsa_circ_0000722 is up-regulated in greater omentum adipose tissue from obese individuals. It was included in a ceRNA network and predicted to regulate metabolic gene G6PD via sponging hsa-miR-326_R+1.
Confidence score:

0.4032
Other information
Title:

Noncoding RNA profiling in omentum adipose tissue from obese patients and the identification of novel metabolic biomarkers.

Journal: Frontiers in genetics
Published: 2025
PubMed ID: 39981261
Study type:

combined biological and clinical study
Data availability: GSE286454
Code availability: -