circRNA basic information
circBase ID: -
Name: -
Synonym: circ_004103
Host Gene: -
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005233
MONDO name: non-small cell lung carcinoma
Disease details: non-small cell lung cancer / NSCLC
Disease DO ID:
 3908
Disease MeSH ID:
 D002289
Disease NCIt ID:
 C2926
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

lung cancer tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DS
Associated gene: -
Associated microRNA: -
Biological function: Associated by bioinformatic pathway enrichment with Ras signaling pathway and PI3K-Akt signaling pathway in the context of EGFR mutation mechanisms in NSCLC.
Molecular mechanism: Bioinformatics-predicted pathway involvement in Ras signaling pathway and PI3K-Akt signaling pathway based on circRNA/mRNA relation pairs.
Biological pathway or process:

PI3K/AKT (other); other pathway/process (other)
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

-
Description:

circ_004103 was identified among circRNAs implicated by KEGG pathway enrichment in EGFR mutation-related NSCLC analysis. Its predicted associations were Ras signaling and PI3K-Akt signaling, but no experimental validation or specific expression direction was reported.
Confidence score:

0.1768
Other information
Title:

Epidermal Growth Factor Receptor Mutation Mechanisms in Nonsmall Cell Lung Cancer by Transcriptome Sequencing.

Journal: Cancer biotherapy & radiopharmaceuticals
Published: 2022
PubMed ID: 34009009
Study type:

bioinformatics study
Data availability: All data generated or analyzed during this study are included in this published article.
Code availability: -