circRNA basic information
circBase ID: -
Name: hsa_circ_CWF19L1
Synonym: EV-circCWF19L1
Host Gene: CWF19L1
Genomic location(hg19): -
Genomic location(hg38): -
Subcellular localization: extracellular vesicle
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0001056
MONDO name: gastric cancer
Disease details: gastric cancer / GC
Disease DO ID:
 10534
Disease MeSH ID:
 -
Disease NCIt ID:
 C9331
Disease ICD11 ID:
 1397617262
Disease OMIM ID:
 613659
Species: Human
Species details: Homo sapiens
Tissue specimen:

plasma
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: biomarker for gastric cancer detection/diagnosis (four-marker EV-circRNA panel)
Molecular mechanism: not specified
Biological pathway or process:

not specified
Detected method:
Others
Validation methods:

Clinical Sample Validation; Cohort Study; ROC Analysis; Bioinformatics Analysis
Clinical significance:

Part of a four EV-circRNA biomarker panel measured in plasma EVs to distinguish healthy donors from gastric cancer patients and aid early diagnosis using BEISA plus machine learning.
Description:

EV-circCWF19L1 is up-regulated in gastric cancer plasma EVs and is included in a four-circRNA BEISA biomarker panel combined with machine learning for gastric cancer detection and staging.
Confidence score:

0.4484
Other information
Title:

Bimodal In Situ Analyzer for Circular RNA in Extracellular Vesicles Combined with Machine Learning for Accurate Gastric Cancer Detection.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: 2025
PubMed ID: 39823497
Study type:

combined biological and clinical study
Data availability: Research data are not shared.
Code availability: -