circRNA basic information
circBase ID: hsa_circ_0085045
Name: hsa_circ_STK3
Synonym: -
Host Gene: STK3
Genomic location(hg19): chr8:99718694-99761618:-
Genomic location(hg38): chr8:98706466-98749390:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0018874
MONDO name: acute myeloid leukemia
Disease details: acute myeloid leukemia / AML
Disease DO ID:
 9119
Disease MeSH ID:
 D015470
Disease NCIt ID:
 C3171
Disease ICD11 ID:
 -
Disease OMIM ID:
 601626
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: -
Associated microRNA: -
Biological function: In Splice molecular subtype of AML, high expression is associated with poorer survival; associated with complete remission status.
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis; Survival Analysis
Clinical significance:

In the Splice molecular subtype, high expression is associated with poorer patient survival.
Description:

hsa_circ_0085045 (STK3-derived) is a prognostic circRNA in the AML Splice molecular subtype, where higher expression is linked to poorer survival and is associated with complete remission status.
Confidence score:

0.348
Other information
Title:

Landscape of circular RNAs in acute myeloid leukemia and their clinical significance.

Journal: NPJ precision oncology
Published: 2026
PubMed ID: 41787043
Study type:

combined biological and clinical study
Data availability: phs001657.v1.p1; GSE158596; https://zenodo.org/records/7274740; 10.5281/zenodo.292986
Code availability: -