circRNA basic information
circBase ID: hsa_circ_0009361
Name: hsa_circ_GNB1
Synonym: circGNB1
Host Gene: GNB1
Genomic location(hg19): chr1:1749275-1770677:-
Genomic location(hg38): chr1:1817836-1839238:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005575
MONDO name: colorectal cancer
Disease details: colorectal cancer / CRC
Disease DO ID:
 5672, 9256
Disease MeSH ID:
 -
Disease NCIt ID:
 C4978
Disease ICD11 ID:
 -
Disease OMIM ID:
 114500
Species: Human
Species details: Homo sapiens
Tissue specimen:

CRC tissue samples; adjacent control tissues
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: unknown
Molecular mechanism: unknown
Biological pathway or process:

not specified
Detected method:
Q
Validation methods:

RT-qPCR; Clinical Sample Validation; ROC Analysis
Clinical significance:

Down-regulated in CRC tissues and shows diagnostic value (AUC 0.85).
Description:

hsa_circ_0009361 is significantly down-regulated in colorectal cancer tissues versus paired adjacent control tissues and shows diagnostic potential in distinguishing CRC from controls (AUC 0.85).
Confidence score:

0.4187
Other information
Title:

Investigation of GNB1 derivative circular RNAs hsa_circ_0009361 and hsa_circ_0009362 expressions in colorectal cancer patients: potential new diagnostic factors.

Journal: Gastroenterology and hepatology from bed to bench
Published: 2024
PubMed ID: 38737931
Study type:

clinical study
Data availability: -
Code availability: -