circRNA basic information
circBase ID: hsa_circ_0008234
Name: -
Synonym: hsa_circ_000823
Host Gene: -
Genomic location(hg19): chr3:71090478-71102924:-
Genomic location(hg38): chr3:71041327-71053773:-
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005233
MONDO name: non-small cell lung carcinoma
Disease details: non-small cell lung cancer / NSCLC
Disease DO ID:
 3908
Disease MeSH ID:
 D002289
Disease NCIt ID:
 C2926
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

NSCLC tissue; adjacent healthy tissue; tumor-adjacent tissue
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
DN
Associated gene: -
Associated microRNA: 43 types of miRNAs
Biological function: Predicted differentially expressed tumor suppressor circRNA in NSCLC, potentially acting through miRNA sponge/ceRNA-related regulation of cell cycle, inflammatory response, and proliferation.
Molecular mechanism: Predicted miRNA sponge mechanism based on CSCD database functional analysis.
Biological pathway or process:

ceRNA regulation (other); proliferation (inhibits); cell cycle (other); inflammation (other)
Detected method:
M
Validation methods:

Microarray; Bioinformatics Analysis
Clinical significance:

Potential molecular marker for NSCLC based on bioinformatics prediction.
Description:

hsa_circ_0008234 was identified as downregulated in NSCLC tissues from GEO microarray datasets. The study only provides bioinformatics-level evidence, predicting that it may bind multiple miRNAs and may participate in tumor suppressor-related ceRNA processes.
Confidence score:

0.1768
Other information
Title:

Bioinformatics Analysis Predicts hsa_circ_0026337/miR-197-3p as a Potential Oncogenic ceRNA Network for Non-Small Cell Lung Cancers.

Journal: Anti-cancer agents in medicinal chemistry
Published: 2022
PubMed ID: 34254931
Study type:

bioinformatics study
Data availability: GSE158695; GSE112214; GSE101684; CSCD
Code availability: -