circRNA basic information
circBase ID: -
Name: hsa_circ_BPTF
Synonym: circBPTF / circ-BPTF
Host Gene: BPTF
Genomic location(hg19): chr17:65941525-65972074:.
Genomic location(hg38): chr17:67945409-67975958:.
Subcellular localization: not tested
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0002602
MONDO name: central nervous system disorder
Disease details: oxidative stress
Disease DO ID:
 331
Disease MeSH ID:
 D002493
Disease NCIt ID:
 C2934
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

-
Cell lines:

SH-SY5Y
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UN
Associated gene: AJAP1
Associated microRNA: miR-138-5p
Biological function: hub circRNA in the PD-OS ceRNA network, potentially regulating mRNAs via miRNA sponging
Molecular mechanism: ceRNA (circRNA-miRNA-mRNA) network via miRNA sponging
Biological pathway or process:

ceRNA regulation (other)
Detected method:
S
Validation methods:

RNA-seq; Bioinformatics Analysis
Clinical significance:

-
Description:

circBPTF is a top hub circRNA in the PD-OS ceRNA network in SH-SY5Y cells, predicted to regulate AJAP1 via sponging miR-138-5p as part of a circRNA-miRNA-mRNA regulatory axis.
Confidence score:

0.1768
Other information
Title:

Oxidative Stress-Associated Alteration of circRNA and Their ceRNA Network in Differentiating Neuroblasts.

Journal: International journal of molecular sciences
Published: 2024
PubMed ID: 39596524
Study type:

biological research
Data availability: GSE161860; GSE182627
Code availability: -