| Expression pattern: |
UN |
| Associated gene: |
YBX1 |
| Associated microRNA: |
- |
| Biological function: |
Potential extracellular vesicle marker (enriched in EVs with high back-splicing ratio). |
| Molecular mechanism: |
RBP-associated sorting into EVs via interaction with YBX1. |
| Biological pathway or process: |
other pathway/process (other) |
| Detected method: |
Q
S
|
| Validation methods: |
RNA-seq; RT-qPCR; RIP (RNA Immunoprecipitation) |
| Clinical significance: |
Potential marker for distinguishing EVs from other tissue/cell components. |
| Description: |
circSMARCA5 is highly prevalent and enriched in extracellular vesicles, showing higher EV abundance than its linear host gene. It can serve as a potential EV marker and is associated with RBP-mediated sorting through interaction with YBX1. |
| Confidence score: |
0.3401 |