circRNA basic information
circBase ID: hsa_circ_0033861
Name: hsa_circ_ADAM6
Synonym: -
Host Gene: ADAM6
Genomic location(hg19): chr14:106331860-106765065:-
Genomic location(hg38): chr14:105865650-106308804:-
Subcellular localization: exosome
 
 
 
 
 
 
 
Disease basic information
MONDO ID:
 0005061
MONDO name: lung adenocarcinoma
Disease details: lung adenocarcinoma / LUAD
Disease DO ID:
 3910
Disease MeSH ID:
 C538231
Disease NCIt ID:
 C3512
Disease ICD11 ID:
 -
Disease OMIM ID:
 -
Species: Human
Species details: Homo sapiens
Tissue specimen:

plasma exosome
Cell lines:

-
In vivo animal model:

-
circRNA-disease information
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Biological pathway or process:

not specified
Detected method:
Q
M
Validation methods:

Microarray; RT-qPCR; RNase R Treatment; Clinical Sample Validation; Bioinformatics Analysis
Clinical significance:

potential diagnostic biomarker for LUAD
Description:

circ-0033861 (circADAM6) is significantly upregulated in plasma exosomes from LUAD patients versus healthy controls (microarray and RT-qPCR). The study suggests it may serve as a circulating, non-invasive diagnostic biomarker candidate for LUAD.
Confidence score:

0.5135
Other information
Title:

Identification of a Plasma Exosomal lncRNA- and circRNA-Based ceRNA Regulatory Network in Patients With Lung Adenocarcinoma.

Journal: The clinical respiratory journal
Published: 2024
PubMed ID: 39428538
Study type:

combined biological and clinical study
Data availability: The data in this study can be obtained under reasonable conditions by contacting Dr. Wangyu Zhu (email: zhuwangyu24@sina.cn).
Code availability: -